Fundamentals In Immunology and Infection

Learning goals:  

• Identify the organization of the body’s defenses against pathogens: from innate to adaptive immunity.
• Describe the ontogeny of cells of the innate and acquired immune system, their relevance and how they interact during an immune response.
• Understand how the immune system senses danger and how that initiates an immune response.
• Recognize the immune system’s antimicrobial mechanisms: from toxic intermediate to cell death.
• Identify the major T cell phenotypes, the cytokines and transcription factors required for their differentiation and function.
• Recognize the importance of the metabolic choices of different immune cell subsets.
• Recognize the impact of the microenvironment in T cell function.
• Identify Mendelian and complex susceptibility to infectious diseases.
• Define strategies for genome variation analyses.

More information: www.med.uminho.pt/en/Post-Graduation/courses/fii