Explore and discuss the importance of metabolism in the function of immune cells and the mechanisms whereby the microbiome or the pathophysiology of infectious and neurological diseases, and cancer shape immune cell metabolomics.
In recent years, significant advancements in neuroscience tools have provided researchers with a new in-depth perspective on brain function. Novel anatomical, optical, genetic, electrophysiological, and imaging approaches have opened new possibilities for investigating neuronal circuits.
This hands-on course offers advanced training on various tools used for the analysis of neuronal circuits, including neuronal tracing strategies, fiber photometry, calcium/sensor imaging with miniaturized microscopes, in vivo electrophysiology, and opto- and chemo-genetics. The course places a strong emphasis on how to design and develop a correct experiment using these tools, and on the appropriate controls, and on the limitations of these methodologies. This approach ensures that participants comprehend the strengths and limitations of each technique and can design, implement, and interpret experiments correctly. By the end of the course, students will have gained the basic skills and knowledge necessary to undertake innovative research projects in neuroscience.
Single-cell genomics has recently emerged as a revolutionary approach to study the gene expression and the epigenome of individual cells. Therefore, it has shaped our understanding of cellular heterogeneity and it has become a powerful tool to find previously unknown cellular states and populations.